Related Experiment Video
Updated: Aug 23, 2025
06:58
Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
Published on: August 23, 2019
7.1K
Dietary Polysaccharides and Gut Microbiota Ecosystem
Ana I Álvarez-Mercado1,2,3, Julio Plaza-Diaz1,3,4
1Instituto de Investigación Biosanitaria ibs.GRANADA, Complejo Hospitalario Universitario de Granada, 18014 Granada, Spain.
Nutrients
|October 27, 2022
Summary
The intestinal microbiota, a complex community of microorganisms in the gut, plays a crucial role in maintaining gastrointestinal health and overall well-being.
Area of Science:
- Microbiology
- Gastroenterology
- Ecology
Background:
- The intestinal microbiota comprises trillions of microorganisms, including bacteria, archaea, fungi, and viruses, residing in the gastrointestinal tract.
- This complex ecosystem profoundly influences host physiology, metabolism, and immunity.
Discussion:
- The composition and function of the intestinal microbiota are dynamic and influenced by factors such as diet, genetics, and environmental exposures.
- Dysbiosis, an imbalance in the microbial community, is associated with various diseases, including inflammatory bowel disease, obesity, and metabolic disorders.
Key Insights:
- Understanding the intricate interactions between the microbiota and the host is essential for developing targeted therapeutic strategies.
- Recent advancements in sequencing technologies have enabled comprehensive profiling of the gut microbiome, revealing its vast genetic and functional diversity.
Outlook:
- Future research will focus on elucidating causal relationships between specific microbial taxa or functions and disease states.
- The development of microbiome-based diagnostics and therapeutics holds significant promise for personalized medicine and improved health outcomes.
More Related Videos
07:15An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
9.7K
08:24Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
Published on: May 2, 2018
19.7K
Related Concept Videos
01:29Bacterial Flora of the Large Intestine
575
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
575
01:50What is Monogastric Digestion?
72.0K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
72.0K
01:26Biosynthesis of Polysaccharides
60
Polysaccharides such as glycogen and starch are synthesized from nucleoside diphosphate sugars, primarily uridine diphosphate glucose (UDPG) and adenosine diphosphate glucose (ADPG). These activated glucose donors act as key intermediates in carbohydrate metabolism and biosynthesis. UDPG primarily involves glycogen synthesis in animals and many bacteria, while ADPG plays a fundamental role in starch synthesis in plants and certain bacteria.UDPG is formed when glucose-1-phosphate reacts with...
60
01:29Biofilms
195
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
195
01:15Cellulose and Pectic Polysaccharides
3.8K
Every plant cell has a cell wall that protects the cell, provides structural support, and gives the cell shape. Cellulose, the main structural component of the plant cell wall, makes up over 30% of plant matter. It is the most abundant organic compound on earth. Cellulose is an unbranched polysaccharide composed of linear chains of glucose molecules linked by β (1→4) glycosidic bonds.
As a cell matures, its cell wall specializes according to its type. For example, the...
As a cell matures, its cell wall specializes according to its type. For example, the...
3.8K
01:25Carbohydrate Absorption
1.1K
Carbohydrates are essential macronutrients that serve as the body's primary energy source. Their digestion begins in the mouth, where salivary amylase partially breaks down complex carbohydrates such as starch into smaller oligosaccharides. This mechanical and enzymatic activity prepares carbohydrates for further processing in the gastrointestinal tract.
After being swallowed, the partially digested carbohydrates mix with gastric secretions in the stomach. However, the acidic environment...
After being swallowed, the partially digested carbohydrates mix with gastric secretions in the stomach. However, the acidic environment...
1.1K