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Updated: Aug 23, 2025

Super-resolution Imaging of Neuronal Dense-core Vesicles
Published on: July 2, 2014
Super-Resolving Methodology for Noisy Unpaired Datasets
Sung-Jun Min1, Young-Su Jo1, Suk-Ju Kang1
1Department of Electronic Engineering, Sogang University, Seoul 04107, Korea.
Abstract:
Although it is possible to acquire high-resolution and low-resolution paired datasets, their use in directly supervised learning is impractical in real-world applications. In the present work, we focus on a practical methodology for image acquisition in real-world conditions. The main method of noise reduction involves averaging multiple noisy input images into a single image with reduced noise; we also consider unpaired datasets that contain misalignments between the high-resolution and low-resolution images. The results show that when more images are used for average denoising, better performance is achieved in the super-resolution task. Quantitatively, for a fixed noise level with a variance of 60, the proposed method of using 16 images for average denoising shows better performance than using 4 images for average denoising; it shows 0.68 and 0.0279 higher performance for the peak signal-to-noise ratio and structural similarity index map metrics, as well as 0.0071 and 1.5553 better performance for the learned perceptual image patch similarity and natural image quality evaluator metrics, respectively.
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