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Updated: Aug 23, 2025
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Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
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Enteroviral Infections in Infants
Srijan Singh1, Sushant Satish Mane1, Gangajal Kasniya2
1Department of Pediatrics, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.
Newborn (Clarksville, Md.)
|October 28, 2022
Summary
Enteroviruses (EVs) are significant infant pathogens. This review covers their properties, clinical impacts, and diagnostic, treatment, and prognostic methods, focusing on coxsackie and echoviruses.
Area of Science:
- Virology
- Pediatrics
- Infectious Diseases
Background:
- Enteroviruses (EVs) are primary pathogens in infants.
- Traditional classification includes polio, coxsackie A and B, and echoviruses.
- Coxsackie and echoviruses are gaining attention due to structural similarities and translational medicine potential.
Purpose of the Study:
- To review enterovirus properties.
- To detail clinical manifestations and transmission routes.
- To outline current diagnostic, treatment, and prognostic approaches.
Main Methods:
- Literature review of enterovirus research.
- Analysis of clinical presentations and epidemiological data.
- Summary of laboratory diagnostic techniques (RT-PCR, cell culture, serology).
Main Results:
- EVs manifest as viral prodromes, meningitis, encephalitis, myopericarditis, and multi-organ failure.
- Transmission occurs via oral and fecal-oral routes.
- Diagnosis relies on molecular and serological methods.
Conclusions:
- Understanding EV properties is crucial for managing infant infections.
- Current diagnostics and therapeutics offer avenues for prevention and treatment.
- Further research into coxsackie and echoviruses holds translational medicine promise.
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