Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

19
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
19
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

46
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
46
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

29
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
29
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

45
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
45
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

22
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
22
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

25
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
25

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Malperfusion on Presentation Versus Complexity of Operation as Determinants of Early Mortality in Acute Type A Aortic Dissection.

Aorta (Stamford, Conn.)·2026
Same author

Detecting and managing arrhythmic mitral valve prolapse.

Proceedings (Baylor University. Medical Center)·2025
Same author

Delayed Aortic Dissection After Transcatheter Aortic Valve Replacement for Stenotic Bicuspid Valve.

The American journal of cardiology·2025
Same author

Acute Ascending Aortic Dissection Masquerading as an ST Elevation Myocardial Infarction.

The American journal of cardiology·2024
Same author

Type A Aortic Dissection After Thoracic Endovascular Aortic Repair for Type B.

The American journal of cardiology·2024
Same author

The Congenitally Malformed Aortic Valve in Type A Aortic Dissection: Its Frequency and Consequences.

The American journal of cardiology·2024
Same journal

Beyond timing: mobility may be the missing variable in venous thromboembolism prevention after traumatic brain injury.

Proceedings (Baylor University. Medical Center)·2026
Same journal

Beyond comorbidity scores: medication burden as a window into surgical risk following ankle fracture fixation.

Proceedings (Baylor University. Medical Center)·2026
Same journal

The risk of primary lung cancer in ANCA-associated vasculitis: systematic review and meta-analysis.

Proceedings (Baylor University. Medical Center)·2026
Same journal

Clinical presentation and treatment of a case of anti-signal recognition particle-positive immune-mediated necrotizing myopathy.

Proceedings (Baylor University. Medical Center)·2026
Same journal

Nationwide analysis of adult nongonococcal native septic knee arthritis hospitalizations from 2016 to 2022.

Proceedings (Baylor University. Medical Center)·2026
Same journal

Comparing the diagnostic performance of 19-gauge and 22-gauge needles in endoscopic ultrasound-guided liver biopsy: a systematic review and meta-analysis.

Proceedings (Baylor University. Medical Center)·2026
See all related articles

Related Experiment Video

Updated: Aug 23, 2025

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

448

Diagnosing aortic syphilis.

Charles S Roberts1,2, William C Roberts2,3,4

  • 1Department of Cardiac Surgery, Baylor University Medical Center, Dallas, Texas.

Proceedings (Baylor University. Medical Center)
|October 28, 2022
PubMed
Summary
This summary is machine-generated.

Aortic syphilis can cause aneurysms in the ascending aorta, even with negative syphilis tests. This diagnosis is likely when aneurysms lack dissection or sinus involvement.

Keywords:
Aortic aneurysmaortic operationaortic syphilis

More Related Videos

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
06:43

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus

Published on: December 7, 2013

13.9K
Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
06:51

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research

Published on: October 20, 2023

1.2K

Related Experiment Videos

Last Updated: Aug 23, 2025

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

448
Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
06:43

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus

Published on: December 7, 2013

13.9K
Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
06:51

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research

Published on: October 20, 2023

1.2K

Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Aortic aneurysms are a significant cause of morbidity and mortality.
  • Syphilis, a curable sexually transmitted infection, can affect the cardiovascular system, leading to syphilitic aortitis and aneurysms.
  • The prevalence of syphilitic aortitis has declined but remains a relevant clinical entity.

Observation:

  • A case study of a 57-year-old morbidly obese male presenting with an aneurysm of the tubular aorta.
  • Surgical resection of the aneurysm revealed classic histopathological findings consistent with syphilitic aortitis.
  • The patient's presentation involved an aneurysm of the ascending aorta without evidence of aortic dissection or involvement of the sinuses of Valsalva.

Findings:

  • Aortic syphilis should be considered in the differential diagnosis of ascending aortic aneurysms, particularly when dissection or sinus of Valsalva involvement is absent.
  • Serologic tests for syphilis may be negative in cases of established syphilitic aortitis, complicating diagnosis.
  • Histopathological examination of resected aortic tissue is crucial for confirming the diagnosis of aortic syphilis.

Implications:

  • This case highlights the importance of considering aortic syphilis in patients with unexplained ascending aortic aneurysms, irrespective of traditional syphilis testing results.
  • Clinicians should maintain a high index of suspicion for syphilitic aortitis, especially in endemic areas or in specific patient populations.
  • Early recognition and treatment of syphilitic aortitis are essential to prevent catastrophic complications such as aortic rupture or dissection.