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A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

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Nitrofurantoin-Induced Exfoliative Dermatitis: A Case Report.

Carolina Morna¹, Jéssica Chaves¹, Carolina Barros¹

¹Internal Medicine, Hospital Dr. Nélio Mendonça, Funchal, PRT.

|October 31, 2022

Summary

Exfoliative dermatitis (ED) is a rare emergency. A case report details a patient who recovered fully from drug-induced ED after nitrofurantoin withdrawal and treatment.

Keywords:

drug reaction erythroderma exfoliative dermatitis hypersensitivity reaction nitrofurantoin

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Published on: September 27, 2017

Area of Science:

Dermatology
Pharmacology
Internal Medicine

Background:

Exfoliative dermatitis (ED) is a severe dermatological condition with diverse etiologies, including drug reactions.
Prompt diagnosis and management are crucial due to its potentially life-threatening nature.

Observation:

A 77-year-old male presented with exfoliative dermatitis five days after initiating nitrofurantoin therapy.
The patient's condition was attributed to a drug reaction to nitrofurantoin.

Findings:

Discontinuation of nitrofurantoin was followed by topical corticosteroid treatment and supportive care.
The patient experienced a complete recovery from exfoliative dermatitis within one week.

Implications:

This case highlights nitrofurantoin as a potential cause of exfoliative dermatitis.
Early recognition and withdrawal of the offending drug are key for favorable outcomes in drug-induced exfoliative dermatitis.