Related Experiment Video
Updated: Aug 23, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
High resolution anterior segment optical coherence tomography of ocular surface lesions: A review and handbook
Nandini Venkateswaran1, Carolina Mercado2, Sarah C Wall2
1Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
Introduction:
High resolution anterior segment optical coherence tomography (HR-OCT) has revolutionized the way by which clinicians can diagnose and differentiate ocular surface lesions. Careful interpretation of HR-OCT images can provide morphological information about the lesion of interest and help guide the diagnosis.
Areas Covered:
This paper reviews the steps to interpreting HR-OCT images of ocular surface lesions and summarizes their characteristic findings.
Expert Opinion:
Among the multiple modalities available to image the ocular surface and anterior segment, HR-OCT has emerged as an instrumental tool to obtain "optical biopsies" of various ocular surface lesions. A step-by-step approach to acquiring and interpreting HR-OCT images can allow for accurate in-office characterization and diagnosis of both benign and malignant ocular surface lesions.
Related Concept Videos
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment

