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Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
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A Brief Report on Monkeypox Outbreak 2022: Historical Perspective and Disease Pathogenesis
Partha Pratim Deb Chowdhury1, Md Anamul Haque1, Bulbul Ahamed1
1Department of Pharmacy, University of Asia Pacific, Dhaka, Bangladesh.
Clinical Pathology (Thousand Oaks, Ventura County, Calif.)
|October 31, 2022
Summary
The 2022 monkeypox (MPXV) outbreak spread globally, causing public health concern. This report reviews MPXV epidemiology, transmission, and recommends using smallpox vaccines and antivirals.
Area of Science:
- Epidemiology
- Virology
- Public Health
Background:
- Monkeypox (MPXV) is a zoonotic disease endemic in Africa, which rapidly spread globally in 2022.
- The World Health Organization declared MPXV a global health emergency due to its multi-country outbreak.
- The MPXV outbreak intensified pressure on healthcare systems already strained by the COVID-19 pandemic.
Purpose of the Study:
- To provide a brief report on the 2022 MPXV outbreak.
- To review available epidemiological data and transmission patterns.
- To recommend public health strategies and therapeutic approaches for MPXV.
Main Methods:
- Data extraction from Scopus, PubMed, and relevant website databases.
- Manual review of all identified articles.
- Analysis of epidemiological data and transmission factors.
Main Results:
- MPXV spread to over 100 countries, impacting global healthcare systems.
- Epidemiological data suggests sexual orientation and encounters as potential contributing factors, though MPXV is not classified as an STI.
- MPXV exhibits diverse transmission routes beyond sexual contact.
Conclusions:
- Effective prevention, social awareness, and therapeutic strategies are crucial to manage the MPXV burden.
- Focusing solely on sexual transmission risks may increase stigma and hinder control efforts.
- Repurposing existing smallpox vaccines and antivirals is recommended for MPXV management pending specific treatments.
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