Health economic modeling for Alzheimer's disease: Expert perspectives

Area of Science:

• Health Economics
• Neurodegenerative Diseases
• Pharmacoeconomics

Background:

• Accurate economic evaluation of Alzheimer's disease (AD) interventions is vital for policy and payer decisions.
• Expanding knowledge of AD and potential disease-modifying treatments necessitate updated economic modeling approaches.
• Current economic models require clear specifications to incorporate new diagnostic and therapeutic advancements.

Purpose of the Study:

• To provide expert consensus on the structure, validation, and reporting of future economic models for AD.
• To identify essential data requirements for populating advanced AD economic models.
• To foster discussion on the detailed specifications for health economic models in Alzheimer's disease research.

Main Methods:

• This perspective synthesizes expert opinions from health economists and governmental agency representatives.
• The article focuses on defining specifications for future economic models for AD interventions.
• Expert insights guide the discussion on structuring, validating, and reporting these models.

Main Results:

• Key considerations for future AD economic models include data needs, validation standards, and reporting guidelines.
• Expert opinion highlights the need for adaptable models that can incorporate evolving AD diagnostics and therapeutics.
• A consensus is emerging on the critical elements required for robust economic evaluations in AD.

Conclusions:

• Future economic models for Alzheimer's disease interventions require careful specification and validation.
• Collaboration between health economists and policymakers is essential for developing reliable economic evaluations.
• Standardized approaches to economic modeling will support evidence-based decision-making for AD treatments.