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Updated: Aug 23, 2025

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Published on: March 13, 2017
The eutectic point in choline chloride and ethylene glycol mixtures
Hannah J Hayler1, Susan Perkin1
1Physical and Theoretical Chemistry Laboratory, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK. susan.perkin@chem.ox.ac.uk.
Abstract:
The choline chloride (ChCl) and ethylene glycol (EG) mixture has become established as a paradigmatic deep eutectic solvent (DES). Here, we present measurements of the phase behaviour of this mixture over a wide composition range, and provide an extended phase diagram. The eutectic point was found to lie at -28 ± 1 °C and 0.01 < xChCl < 0.02, sharply contrasting with the previously expected eutectic composition. Our observations confirm that the eutectic temperature is not 'deep' compared to the ideal solution theory prediction. We also observe a cold-crystallisation at T = -65 °C which may have been formerly misinterpreted as the eutectic point.
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