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Updated: Aug 23, 2025
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Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
Published on: April 6, 2022
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Probiotics and gastrointestinal diseases.
Vanessa N Dargenio1, Stefania Castellaneta1, Serena Panico1
1Section of Pediatrics, Interdisciplinary Department of Medicine, Giovanni XXIII Children's Hospital, University of Bari Aldo Moro, Bari, Italy.
Minerva Pediatrics
|October 31, 2022
Summary
The gut microbiome
Area of Science:
- Microbiology
- Gastroenterology
- Human Health
Background:
- The gut microbiome plays a crucial role in human health.
- Biotics (probiotics, prebiotics, synbiotics, and postbiotics) are investigated for health benefits.
- Evidence for biotics' efficacy varies by condition and administration.
Purpose of the Study:
- To summarize current evidence on probiotics for specific gastrointestinal diseases.
- To assess the progress and remaining questions in the field of biotics for gut health.
Main Methods:
- Literature review of studies on probiotics in gastrointestinal diseases.
- Analysis of evidence based on indication, strain, dosage, and duration.
Main Results:
- Evidence for probiotics is inconsistent across different gastrointestinal conditions.
- Further research is needed to clarify optimal use of probiotics.
- Specific gastrointestinal diseases reviewed include infantile colic, functional abdominal pain, celiac disease, gastroenteritis, IBD, and H. pylori infection.
Conclusions:
- The use of probiotics in gastrointestinal diseases shows potential but requires more research.
- Optimal probiotic use (strain, dose, duration) remains an open question.
- The field of gut microbiome and biotics is evolving, representing a new starting point.
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