Related Experiment Video

Updated: Aug 23, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

19.9K

Down Syndrome children with obstructive sleep apnea

Angela Militi1, Riccardo Nucera1, Giusy Chirieleison1

  • 1Department of Biomedical, Dental Science and Morphological and Functional Images, University of Messina, Messina, Italy.

Minerva Dental and Oral Science
|November 2, 2022
PubMed

Insights

Obstructive sleep apnea syndrome (OSAS) is more common and severe in children with Down syndrome (DS). Early screening and treatment for OSAS in DS patients are recommended, though predictors are lacking.

Area of Science:

  • Pediatrics
  • Genetics
  • Sleep Medicine

Background:

  • Obstructive sleep apnea syndrome (OSAS) presents significant clinical challenges for individuals with Down syndrome (DS).
  • OSAS is notably more prevalent and severe in the DS population compared to the general population.

Purpose of the Study:

  • To review the literature on the prevalence and severity of OSAS in children with Down syndrome.
  • To assess the utility of screening and treatment for OSAS in this population.
  • To identify potential associations between sleep disturbances and daily living activities in children with DS.

Main Methods:

  • A comprehensive literature search was conducted across PubMed, Google Scholar, and the Cochrane Library.
  • Nine studies were selected for evaluation based on predefined inclusion criteria.

Main Results:

  • Adolescents with Down syndrome exhibit a high comorbidity of OSAS.
  • Evidence supports the benefit of widespread screening and treatment of OSAS in children with DS.
  • Sleep disturbances are linked to functional daily living activities in children with DS.

Conclusions:

  • Children with Down syndrome have higher rates and severity of OSAS.
  • Currently, no reliable clinical predictors for OSAS exist specifically for children with DS.
Abstract

More Related Videos

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

874
Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

2.4K

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
208
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
118
Meiosis I01:49

Meiosis I

Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each containing half the number of chromosomes present in somatic cells elsewhere in the body. Meiosis I is the first such division, and involves several key steps, among them: condensation of replicated chromosomes in diploid cells; the pairing of homologous chromosomes and their exchange of information; and finally, the separation of homologous chromosomes by...
194.0K
Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
60.1K
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
196
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
187