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Risk factors and management of adverse events in tooth extraction among medically compromised patients
Giath Gazal1,2, Mohammad Z Nassani3, Salah Sakka4
1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Aleppo University, Aleppo, Syria.
Abstract:
Tooth extraction in medically compromised adults presents significant clinical challenges due to an increased risk of bleeding, infection, delayed healing, and systemic complications. The review indicated that Diabetes mellitus affects 8-12% of dental patients and is associated with a 10-15% risk of intraoperative hypoglycemia, while anticoagulated patients experience postoperative bleeding in 8-12% of cases compared with 2-3% in controls. Hypertension affects up to 30% of adults, leading to perioperative blood pressure elevations in 20-25%, and asthma or chronic obstructive pulmonary disease COPD occurs in 7-10% of patients with a 3-6% risk of bronchospasm. Immunosuppressed and transplant patients show postoperative infection rates as high as 20%. Five structured tables summarize medical classifications, safe clinical thresholds, emergency management, referral criteria, and a stepwise safety ladder for pre-, intra-, and postoperative care. The review emphasizes the importance of strict risk stratification and adherence to validated clinical cut-offs, including HbA1c <9%, INR ≤3.5, and blood pressure <180/110 mmHg. Implementation of standardized safety ladders and evidence-based thresholds can enhance patient safety, improve decision-making, and promote global consistency in managing medically compromised dental patients.
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