Associations Between Race/Ethnicity, Language, and Enrollment on Cancer Research Studies
Ogochukwu M Ezeoke1,2,3, Gary Brooks2, Michael A Postow3,4
1Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital, Chicago, IL, USA.
The Oncologist
|November 2, 2022
Summary
Patient race/ethnicity and preferred language impact oncology research enrollment. Non-Hispanic Black patients and minority groups faced lower enrollment rates, highlighting disparities in cancer research participation.
Area of Science:
- Oncology
- Clinical Trials
- Health Disparities
Background:
- Patient enrollment in oncology research is crucial for advancing cancer care.
- Understanding factors influencing enrollment is key to equitable research participation.
Purpose of the Study:
- To investigate associations between patient demographics (race/ethnicity, preferred language) and oncology research enrollment.
- To identify disparities in research participation within a large cancer center population.
Main Methods:
- Retrospective cross-sectional analysis of adult patients (2005-2015) at a metropolitan cancer center.
- Examined enrollment variations by race/ethnicity, preferred language, comorbidities, gender, and age.
- Utilized logistic regression to model enrollment predictors.
Main Results:
- Nearly 40% of 233,604 patients were enrolled in research studies.
- Patients identifying as Native, Other, Unknown, or Refuse to Answer race/ethnicity were less likely to enroll.
- English preferred language and comorbidities were associated with higher enrollment likelihood.
- Non-Hispanic Black patients, despite having comorbidities and English preference, showed lower enrollment rates compared to Non-Hispanic White patients.
Conclusions:
- Significant differences in oncology research enrollment exist based on race/ethnicity and preferred language.
- Non-Hispanic Black patients experience lower enrollment odds, indicating a need for targeted interventions.
- Addressing language diversity is critical to reducing disparities in cancer research participation.
Keywords:
cancer research studiesclinical trialshealthcare disparitieslanguage barrierslanguage equityMore Related Videos
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