Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cell Migration01:09

Cell Migration

17.1K
Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
17.1K
Cell Motility through Blebbing01:16

Cell Motility through Blebbing

2.0K
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
Blebbing Through the Matrix
In multicellular...
2.0K
Cells Coordinate Growth and Proliferation02:36

Cells Coordinate Growth and Proliferation

4.6K
Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...
4.6K
Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

6.1K
Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
6.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrating theory and machine learning to reveal determinants of plasmid copy number.

Nature communications·2026
Same author

Mapping single-cell responses to population-level dynamics during antibiotic treatment.

Molecular systems biology·2026
Same author

A foundation model for microbial growth dynamics.

bioRxiv : the preprint server for biology·2026
Same author

Spatial proximity dictates bacterial competition and expansion in microbial communities.

Nature communications·2025
Same author

Emergence of population-level feedback control by transposon-plasmid coevolution.

bioRxiv : the preprint server for biology·2025
Same author

Scaling laws of bacterial and archaeal plasmids.

Nature communications·2025
Same journal

Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys.

eLife·2026
Same journal

Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses during inflammation.

eLife·2026
Same journal

Restraint of melanoma progression by cells in the local skin environment.

eLife·2026
Same journal

Brawn before bite in endemic Asian eutherian mammals after the end-Cretaceous extinction.

eLife·2026
Same journal

Experimental evolution to thermal stress indicates climate resilience in a cosmopolitan arthropod.

eLife·2026
Same journal

Correlates of protection against African swine fever virus identified by a systems immunology approach.

eLife·2026
See all related articles

Related Experiment Video

Updated: Aug 23, 2025

Quantitative Analysis of Cell Edge Dynamics during Cell Spreading
10:54

Quantitative Analysis of Cell Edge Dynamics during Cell Spreading

Published on: May 22, 2021

5.5K

Bringing cells to the edge.

Teng Wang1, Lingchong You1

  • 1Department of Biomedical Engineering and the Center for Quantitative Biodesign, Duke University, Durham, United States.

Elife
|November 2, 2022
PubMed
Summary
This summary is machine-generated.

Lab-grown Pseudomonas aeruginosa colonies develop open channels for cell and molecular transport. These channels aid in the eradication of competing microbial species.

Keywords:
Pseudomonas aeruginosaStaphylococcus aureusbacteriainterfacial mechanicslong-range transportpattern formationphysics of living systems

More Related Videos

Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy
05:50

Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy

Published on: November 1, 2021

2.4K
Migratory Behavior of Cells Generated in Ganglionic Eminence Cultures
06:34

Migratory Behavior of Cells Generated in Ganglionic Eminence Cultures

Published on: April 21, 2011

10.2K

Related Experiment Videos

Last Updated: Aug 23, 2025

Quantitative Analysis of Cell Edge Dynamics during Cell Spreading
10:54

Quantitative Analysis of Cell Edge Dynamics during Cell Spreading

Published on: May 22, 2021

5.5K
Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy
05:50

Measuring Cell-Edge Protrusion Dynamics during Spreading using Live-Cell Microscopy

Published on: November 1, 2021

2.4K
Migratory Behavior of Cells Generated in Ganglionic Eminence Cultures
06:34

Migratory Behavior of Cells Generated in Ganglionic Eminence Cultures

Published on: April 21, 2011

10.2K

Area of Science:

  • Microbiology
  • Cell Biology
  • Bioengineering

Background:

  • Pseudomonas aeruginosa forms complex colonial structures in vitro.
  • Inter-colony communication and resource competition are critical in microbial ecosystems.

Discussion:

  • The study identifies a network of open channels facilitating intercellular transport within Pseudomonas aeruginosa colonies.
  • These channels enable the movement of cells and molecular cargo from the colony's center to its periphery.

Key Insights:

  • The discovered channel network plays a crucial role in the spatial organization and function of Pseudomonas aeruginosa colonies.
  • This transport system is instrumental in the competitive advantage of Pseudomonas aeruginosa, aiding in the displacement of competing microbial species.

Outlook:

  • Further research could explore the genetic and molecular mechanisms regulating channel formation.
  • Understanding this transport system may offer novel strategies for controlling bacterial populations in various environments.