Related Experiment Video
Updated: Aug 23, 2025
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
18.3K
Refractory Headaches
Olivia Begasse de Dhaem1,2, Paul Rizzoli3
1Headache Specialist at Hartford HealthCare, Hartford, Connecticut.
Seminars in Neurology
|November 2, 2022
Summary
Medication overuse headache (MOH) treatment can be managed without withdrawal. New daily persistent headache (NDPH) and persistent refractory headache after SARS-CoV-2 infection require careful diagnosis and management.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Medication overuse headache (MOH), new daily persistent headache (NDPH), and persistent refractory headache following SARS-CoV-2 infection pose significant challenges in diagnosis and treatment.
- These conditions substantially impact patient disability and quality of life.
Purpose of the Study:
- To review current understanding and treatment strategies for MOH, NDPH, and post-SARS-CoV-2 headaches.
- To highlight the efficacy of preventive treatments for chronic migraine with MOH and discuss NDPH management options.
Main Methods:
- Literature review of studies on MOH, NDPH, and post-viral headaches.
- Analysis of treatment outcomes for various preventive medications and interventions.
Main Results:
- Prevention of MOH is effective whether or not medication withdrawal occurs.
- Preventive treatments like topiramate, onabotulinumtoxinA, and CGRP monoclonal antibodies are beneficial for chronic migraine with MOH.
- No specific guidelines exist for NDPH, but treatments like steroids, nerve blocks, and various medications show potential.
- Headache persistence 3 months post-SARS-CoV-2 infection indicates a poor prognosis.
Conclusions:
- MOH management can prioritize prevention over withdrawal, with several effective preventive options available.
- NDPH diagnosis requires thorough differential examination, and treatment is individualized.
- Persistent headaches after SARS-CoV-2 infection warrant close monitoring due to prognostic implications.
Related Concept Videos
01:27Angina II: Classification
19
Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
19
01:18Dysrhythmias IV: Characteristics of Bradyarrhythmias
62
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
62
01:23Acute Respiratory Failure-IV
191
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
191
01:26Psychosis: Goals of Pharmacotherapy
188
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
188
01:30Acute Respiratory Failure-III
271
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
271
01:26Patterns of Fever
2.9K
Before understanding the types and patterns of fever, it is essential to know its phases.
2.9K