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Updated: Aug 23, 2025

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Improving diagnostic approaches to cerebrovascular disorders in patients with hypertensive encephalopathy
1Department of Neurology and Reflexology, Institute of Family Medicine, Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine.
Insights
Early neurological examination is crucial for hypertensive encephalopathy (HE) detection in hypertension patients. This helps prevent target organ damage, particularly brain damage, through timely diagnosis and intervention.
Area of Science:
- Neurology
- Cardiovascular Research
- Clinical Diagnostics
Background:
- Ischemic stroke incidence is rising, with increased vascular disease risk factors in younger populations.
- Traditional risk factors like hypertension, dyslipidemia, and diabetes are prevalent in the elderly.
- Hypertensive encephalopathy (HE) poses a significant challenge in managing cerebrovascular disorders.
Purpose of the Study:
- To enhance diagnostic approaches for cerebrovascular disorders in patients with hypertensive encephalopathy (HE).
- To elucidate the pathogenesis mechanisms of HE through comprehensive clinical investigation.
- To improve early detection and management strategies for HE.
Main Methods:
- Qualitative study involving clinical and neurological examinations.
- Neuropsychological assessments including Mini-Mental State Examination, personality, and depression scales.
- Two-stage clinical examination to establish or exclude symptomatic hypertension in 351 patients with Grade 2 hypertension.
Main Results:
- 351 patients (150 men, 201 women) with Grade 2 hypertension and HE were evaluated.
- Exclusion criteria included secondary hypertension, diabetes, cardiac arrhythmias, heart failure, stroke, and myocardial infarction.
- The study focused on identifying HE manifestations in hypertensive patients.
Conclusions:
- Mandatory neurological examination for hypertension patients is essential for HE detection.
- Utilizing modern research methods aids in identifying HE manifestations.
- Early detection of HE prevents target organ damage, especially to the brain.
Background:
Modern research today proves an increase in the incidence of ischemic stroke. Risk factors for vascular disease have become more common among young people. Clinical studies have shown that hypertension, dyslipidemia, and diabetes are traditional risk factors among the elderly. The aim of the study was to improve diagnostic approaches to cerebrovascular disorders in patients with hypertensive encephalopathy (НE) by clarifying the development of pathogenesis mechanisms, based on a comprehensive clinical study.
Materials And Methods:
This qualitative study was carried by clinical and neurological examination; neuropsychological examination (Mini-Mental State Examination, abbreviated multifactorial personality questionnaire, Beck depression scale, Spielberger scale).
Results:
The study was examined 351 patients (150 men, 201 women) with НE in hypertension of 2 degrees. The clinical examination was performed according to a two-stage method, which involves the establishment or exclusion of symptomatic hypertension. The study did not include patients with secondary hypertension, diabetes mellitus, cardiac arrhythmias, and conduction disorders, heart failure who suffered from acute cerebrovascular accident and myocardial infarction.
Conclusion:
The necessity of obligatory examination by a neurologist of patients with arterial hypertension for detection of manifestations of НE with the use of modern research methods, which allows to prevent damage to target organs, and first of all - brain damage, has been proved.
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