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Updated: Aug 23, 2025

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
Published on: December 16, 2022
[Fast-evolving cognitive impairment: a home-based diagnosis]
Luca Barbarossa1, Mariangela Gagliano2, Kristof Major1
1Service de gériatrie et de réadaptation gériatrique, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Neurosyphilis, a syphilis infection of the brain, presents diverse symptoms that can mimic other neurological disorders. Early diagnosis and management are crucial, especially in older adults, despite diagnostic challenges.
Area of Science:
- Neurology
- Infectious Diseases
- Geriatrics
Context:
- Syphilis incidence has risen in Switzerland over the past decade.
- Neurosyphilis symptoms are highly variable and can resemble other neurocognitive disorders.
- Diagnosis and management can be challenging, particularly in elderly patients.
Purpose:
- To highlight the diagnostic and management difficulties associated with neurosyphilis in an older patient.
- To emphasize the importance of considering neurosyphilis in the differential diagnosis of cognitive decline in the elderly.
- To discuss potential pitfalls in diagnosing and managing neurosyphilis.
Summary:
- This case report details the diagnostic journey of an older patient with neurosyphilis, initially suspected during a home visit.
- The patient presented with heterogeneous clinical and neurocognitive symptoms mimicking other conditions.
- The article underscores the complexities in diagnosing and managing neurosyphilis in geriatric populations.
Impact:
- Increased awareness among clinicians regarding the varied presentations of neurosyphilis.
- Improved diagnostic strategies for neurosyphilis in older adults.
- Better patient outcomes through timely and accurate diagnosis and treatment of neurosyphilis.
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