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High-throughput screening strategies for space-based radiation countermeasure discovery
Karson S Putt1, Yuhong Du2, Haian Fu2
1Institute for Drug Discovery, Purdue University, West Lafayette IN 47907 USA.
Life Sciences in Space Research
|November 6, 2022
Summary
Developing new radioprotective drugs is crucial for astronaut safety during deep space missions. High-throughput screening (HTS) offers a promising method to discover novel agents effective against chronic space radiation exposure.
Area of Science:
- Space exploration
- Radiation biology
- Drug discovery
Background:
- Space radiation poses a significant health risk to astronauts on long-duration missions.
- Current spacecraft shielding is insufficient for deep space travel.
- Existing radioprotectors are not optimized for chronic, low-dose space radiation.
Conclusions:
- Implementing HTS strategies is vital for discovering effective radioprotectors for space travel.
- Encourages broader application of drug discovery techniques for astronaut radiation protection.
