Use of antiviral drugs for seasonal influenza: Foundation document for practitioners-Update 2019
Fred Y Aoki1, Upton D Allen2,3,4, Samira Mubareka5
1Medical Microbiology and Pharmacology & Therapeutics, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Abstract:
This document updates the previous AMMI Canada Foundation Guidance (2013) on the use of antiviral therapy for influenza.
Insights
This guidance updates recommendations for antiviral therapy in influenza cases. It provides current best practices for managing influenza infections with antiviral medications.
Area of Science:
- Infectious Diseases
- Virology
- Public Health
Background:
- The 2013 AMMI Canada Foundation Guidance provided previous recommendations.
- Influenza remains a significant public health concern globally.
- Evolving influenza strains and treatment landscapes necessitate updated guidelines.
Purpose of the Study:
- To provide an updated evidence-based guidance on antiviral therapy for influenza.
- To incorporate recent research and clinical data into recommendations.
- To assist healthcare professionals in optimizing influenza management.
Main Methods:
- Systematic review of relevant literature published since the last guidance.
- Expert consensus-based recommendations development.
- Consideration of clinical trial data, epidemiological trends, and resistance patterns.
Main Results:
- The updated guidance reflects current understanding of influenza antiviral efficacy.
- Specific recommendations are provided for different patient populations and influenza strains.
- Guidance addresses appropriate use, duration, and monitoring of antiviral treatment.
Conclusions:
- Antiviral therapy remains a critical component in managing influenza.
- Adherence to updated guidelines can improve patient outcomes and reduce transmission.
- Continuous monitoring of influenza epidemiology and antiviral resistance is essential.
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