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Correction: Fmoc-diphenylalanine hydrogels: understanding the variability in reported mechanical properties
Jaclyn Raeburn1, Guillaume Pont2, Lin Chen1
1Department of Chemistry, University of Liverpool, Crown Street, Liverpool, L69 7ZD, UK. d.j.adams@liverpool.ac.uk.
Soft Matter
|November 8, 2022
Summary
This correction addresses variability in mechanical properties of Fmoc-diphenylalanine hydrogels. It clarifies factors influencing these self-assembling biomaterials for consistent research.
Area of Science:
- Biomaterials Science
- Supramolecular Chemistry
- Materials Engineering
Context:
- Fmoc-diphenylalanine (Fmoc-FF) self-assembles into hydrogels with tunable mechanical properties.
- Previous reports on Fmoc-FF hydrogel mechanical properties exhibited significant variability.
- Understanding and controlling this variability is crucial for reliable applications.
Purpose:
- To correct and clarify the findings presented in the original article regarding Fmoc-FF hydrogel mechanical properties.
- To identify and explain the sources of variability in reported data.
- To provide a more accurate understanding of Fmoc-FF hydrogel behavior.
Summary:
- This correction addresses inconsistencies in the reported mechanical properties of Fmoc-diphenylalanine hydrogels.
- It clarifies that the variability stems from subtle differences in experimental conditions and sample preparation.
- The authors provide revised insights into the factors governing hydrogel stiffness and viscoelasticity.
Impact:
- Ensures greater accuracy and reproducibility in future research involving Fmoc-FF hydrogels.
- Facilitates more reliable design and application of these biomaterials in fields like drug delivery and tissue engineering.
- Enhances the scientific understanding of self-assembling peptide-based hydrogel systems.

