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Papillary Reconstruction using Hyaluronic Acid: A Review
Oral Health & Preventive Dentistry
|November 8, 2022
Summary
Hyaluronic acid injections show promise for reconstructing interdental papilla volume in animal models and humans. While effective in most cases, further high-quality clinical trials are needed to optimize protocols.
Area of Science:
- Periodontology
- Regenerative Medicine
- Dermal Fillers
Background:
- Gaps in the interdental papilla, often due to periodontal disease or trauma, can negatively impact aesthetics and oral health.
- Hyaluronic acid (HA) injections are increasingly explored for soft tissue augmentation, including in periodontal reconstruction.
Approach:
- A systematic review of studies published after 2010, adhering to PRISMA guidelines, was conducted.
- Searched electronic databases and performed hand-searching to identify relevant in vivo studies and case series involving HA for papilla reconstruction.
- Assessed the risk of bias for included studies.
Key Points:
- Nineteen articles were reviewed, revealing significant improvements in papilla volume reconstruction using HA injections in most studies.
- Observed filling percentages varied widely (19%–100%), indicating heterogeneity in techniques and outcomes.
- Patient satisfaction was generally high, with minimal reported side effects and low procedure discomfort.
Conclusions:
- Hyaluronic acid injections appear effective for restoring lost papillary volume.
- Current evidence is limited by a lack of high-level clinical trials.
- Future research should focus on standardizing sample size, HA concentration, injection techniques, and number of sessions.
