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Hypercarbia in a Pediatric Patient With Relapsed Medulloblastoma
Mitchell A Luangrath1, Mariko Sato2, Cody R Tigges1
1Pediatric Critical Care Medicine, University of Iowa, Iowa City, USA.
Insights
Recurrent medulloblastoma in children can manifest as respiratory failure due to brainstem involvement. This case highlights the need to consider central nervous system tumors in pediatric respiratory acidosis.
Area of Science:
- Pediatric Oncology
- Pediatric Neurology
- Respiratory Medicine
Background:
- Medulloblastoma is a common pediatric brain tumor.
- Typical symptoms include increased intracranial pressure and ataxia.
- Relapse is usually detected via surveillance imaging.
Abstract:
Pediatric medulloblastoma is a common form of pediatric brain tumor and typically presents with progressive signs of increased intracranial pressure and ataxia. Relapse of the disease is most often diagnosed on surveillance imaging. We present the case of a 13-year-old boy with a previous history of medulloblastoma who presented with chronic hypercarbic respiratory failure as a symptom of a recurrent tumor. Imaging demonstrated a left cerebellar enhancing mass with leptomeningeal thickness and extension to the posterior medulla oblongata, which is the center for respiratory control. His hypercarbic respiratory failure represents a unique presentation of a central nervous system (CNS) tumor. Thus, this case illustrates the importance of thorough evaluation for CNS tumors involving the brainstem in patients with respiratory acidosis and no clear pulmonary etiology.
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