Fluorescence immunosensor based on functional nanomaterials and its application in tumor biomarker detection

Area of Science:

• Analytical Chemistry
• Biomedical Engineering
• Materials Science

Background:

• Immunosensors detect antigen-antibody binding via transducers.
• Fluorescence immunosensing offers simple, fast, and stable immunoassays.
• Traditional fluorescence immunosensors face limitations in sensitivity and environmental stability.

Purpose of the Study:

• To review nanomaterials' role in constructing advanced fluorescence immunosensors.
• To analyze the significance of nanomaterial-based fluorescent immunosensors for tumor biomarker detection.
• To summarize strategies for improving immunosensor performance and future trends.

Main Methods:

• Introduction to various immunosensor types.
• Discussion of nanomaterials' properties (photostability, catalytic activity, biocompatibility).
• Analysis of functional nanomaterials in fluorescent immunosensor construction.

Main Results:

• Nanomaterials enhance photostability, catalytic properties, and biocompatibility.
• Functional nanomaterials enable the development of stable and sensitive fluorescence immunosensors.
• Improved detection of tumor biomarkers is achievable with these advanced sensors.

Conclusions:

• Nanomaterials are crucial for developing next-generation fluorescence immunosensors.
• These sensors show significant promise for sensitive and stable tumor biomarker detection.
• Future research should focus on further performance enhancement and application expansion.