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Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations

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Published on: January 4, 2018

Continuous-flow self-supported seATRP using a sonicated microreactor.

Suqi Zhang¹, Tanja Junkers², Simon Kuhn¹

¹Department of Chemical Engineering, KU Leuven Celestijnenlaan 200F 3001 Leuven Belgium simon.kuhn@kuleuven.be.

Chemical Science

|November 9, 2022

Summary

This summary is machine-generated.

Researchers developed self-supported continuous-flow electrochemically mediated atom transfer radical polymerization (seATRP) without supporting electrolytes. This novel method offers faster reaction rates and improved control for polymer synthesis.

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Area of Science:

Polymer Chemistry
Green Chemistry
Chemical Engineering

Background:

Electrochemically mediated atom transfer radical polymerization (eATRP) offers controlled polymerization.
Traditional eATRP often requires supporting electrolytes, increasing cost and complexity.
Continuous-flow reactors enhance reaction efficiency and scalability.

Purpose of the Study:

To develop a self-supported continuous-flow seATRP system.
To investigate the effect of applied current and sonication on polymerization.
To demonstrate the feasibility of electrolyte-free ATRP in a microreactor.

Main Methods:

Utilized a novel sonicated tubular microreactor for continuous-flow polymerization.
Performed seATRP of acrylic monomers without supporting electrolytes.
Varied applied currents and sonication conditions.

Main Results:

Achieved the first self-supported continuous-flow seATRP.
Demonstrated rapid polymerization with 75% conversion in <27 minutes at ambient temperature.
Obtained good molecular weight evolution and narrow molecular weight distribution.
Showed that reaction rate and control can be tuned by applied current and sonication.

Conclusions:

Self-supported seATRP in a sonicated microreactor is a viable, efficient, and controllable polymerization technique.
Eliminating supporting electrolytes leads to more environmentally friendly and cost-effective polymer synthesis.
This method advances controlled radical polymerization in continuous-flow systems.