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Updated: Aug 22, 2025

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Published on: August 11, 2023
[Dysphagia with no obvious cause: globus pharyngeus]
Eugénie Delaine1, Asimakis Asimakopoulos1, Andrea Avagnina1
1Service ORL et chirurgie cervicofaciale, Centre hospitalier du Valais romand, 1951 Sion.
Globus pharyngeus, a common throat sensation of a lump, often requires no specific tests. Initial treatment involves proton pump inhibitors (PPIs) or reassurance, with speech therapy for persistent cases.
Area of Science:
- Otolaryngology
- Gastroenterology
- Speech Pathology
Context:
- Globus pharyngeus (globus sensation) is a frequent otolaryngology (ENT) referral.
- Characterized by a persistent or intermittent, painless sensation of a lump, foreign body, tightness, or choking in the throat.
- Typically a chronic condition with a tendency for recurrence.
Purpose:
- To outline the diagnostic and management principles for globus pharyngeus.
- To emphasize the importance of clinical history and examination in identifying red flags.
- To provide a stepwise approach to management, including initial medical therapy and subsequent interventions.
Summary:
- Diagnosis relies heavily on thorough patient history and clinical examination to rule out serious conditions.
- Proton pump inhibitors (PPIs) are recommended as a first-line therapeutic trial in the absence of red flags.
- Paraclinical assessments may be considered for non-responsive cases, with reassurance and speech therapy as management options for refractory symptoms.
Impact:
- Provides a clear, evidence-based approach to managing a common yet often frustrating condition.
- Aims to reduce unnecessary investigations and optimize patient care pathways.
- Highlights the multidisciplinary nature of managing globus pharyngeus, involving ENT, gastroenterology, and speech pathology.
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