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Related Concept Videos

Genomics02:02

Genomics

36.9K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genetic Material01:20

Genetic Material

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Within the human body, a complex and detailed system of trillions of cells works in unison to sustain life. Each cell houses a nucleus, which contains 46 chromosomes divided into 23 pairs. Chromosomes are highly coiled structures made of the genetic material DNA. These chromosomes are essential carriers of genetic information, with half inherited from the mother through her egg and the other half from the father's sperm, combining to create the unique genetic makeup of an individual.
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Updated: Aug 22, 2025

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
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GenBank 2023 update.

Eric W Sayers1, Mark Cavanaugh1, Karen Clark1

  • 1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA.

Nucleic Acids Research
|November 9, 2022
PubMed
Summary
This summary is machine-generated.

GenBank is a vast public database of nucleotide sequences, essential for biological research. It ensures worldwide coverage through daily data exchange and offers updated resources for various scientific needs.

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Area of Science:

  • Genomics
  • Bioinformatics
  • Molecular Biology

Background:

  • GenBank is a critical public repository for nucleotide sequences.
  • It collaborates with international archives like ENA and DDBJ for comprehensive data.
  • The database supports a wide range of biological research.

Purpose of the Study:

  • To provide an overview of the GenBank database.
  • To highlight recent updates and new resources.
  • To emphasize its role in global data sharing.

Main Methods:

  • Data aggregation from global nucleotide sequence archives.
  • Regular updates and integration of new biological data.
  • Development of specialized tools and resources for data submission and analysis.

Main Results:

  • GenBank hosts 19.6 trillion base pairs from over 2.9 billion sequences across 504,000 species.
  • Daily data synchronization with ENA and DDBJ ensures global data coverage.
  • New resources include SARS-CoV-2 data, NCBI Datasets, and improved submission tools.

Conclusions:

  • GenBank remains an indispensable resource for genomic data.
  • Continuous updates enhance its utility for researchers worldwide.
  • International collaboration is key to maintaining a comprehensive sequence database.