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Updated: Aug 22, 2025

Author Spotlight: Exploring the Lifespan Dynamics of Healthy Human Hematopoiesis
Published on: December 8, 2023
Allogeneic hematopoietic stem cell transplantation in children and adolescents: ethical problems faced by the
Adriana Ferreira da Silva1, Ulysses Luis Carvalho Kosmaliski1, Bibiana Sales Antunes1
1Universidade Federal do Rio Grande do Sul (UFRGS). Porto Alegre, Rio Grande do Sul, Brasil.
Objective:
To identify the ethical problems faced by the multidisciplinary team in allogeneic hematopoietic stem cell transplantation in children and adolescents.
Method:
Qualitative research inspired by the Convergent Care Research carried out in a Hematopoietic Stem Cell Transplantation Unit in a general hospital in southern Brazil. Fifteen professionals from the multidisciplinary team, intentionally selected, participated. The information was collected through semi-structured interviews and analyzed in the light of the Complex Bioethics Model.
Results:
The health team faces two ethical problems in their daily work: the decision to perform the transplant, and the moment to establish palliative care. In this vulnerable situation of life, children and adolescents need to be welcomed, listened to and respected.
Conclusion:
Professionals are imbued with moral courage to advocate for the patient throughout the therapeutic process, based on reflection on the rights of children and adolescents and respect for the voice in decisions about their care.
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