Related Experiment Video
Updated: Aug 22, 2025
Stereological Estimation of Cholinergic Fiber Length in the Nucleus Basalis of Meynert of the Mouse Brain
Published on: February 5, 2020
Notes on fiber length measurements: A case study in the underbelly of open source neuroscience
Claude J Bajada1, Robert E Smith2, Svenja Caspers3
1Department of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida, Malta; University of Malta MRI Research Platform (UMRI), University of Malta, Msida, Malta.
Abstract:
Being on the bleeding edge of research requires the use of new and regularly updated software. The result is the occasional and inevitable occurrence of bugs. In the following work we present a case study where a feature request introduced a bug in a neuroimaging software package, which had consequences for the quality of results in a published article. We discuss the process of diagnosis, rectification and analysis replication.
