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Coronavirus disease 2019-related Kawasaki syndrome: a case report

Mohammad Hasan Aelami1, Abdolreza Malek1, Amin Saeidinia2,3

  • 1Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Journal of Medical Case Reports
|November 10, 2022
PubMed

Insights

Coronavirus disease 2019 (COVID-19) can present with hyperinflammatory conditions in children, including Kawasaki disease. Early diagnosis and treatment are crucial to prevent severe complications in pediatric patients during the COVID-19 pandemic.

Area of Science:

  • Pediatric infectious diseases
  • Immunology
  • Public health

Background:

  • The COVID-19 pandemic has altered disease patterns in pediatrics.
  • While children are generally less severely affected by COVID-19, hyperinflammatory conditions like Kawasaki disease are a growing concern.
  • This case report focuses on a pediatric patient with Kawasaki disease and concurrent COVID-19 infection.

Observation:

  • An 8-year-old previously healthy Iranian girl presented with a 5-day history of fever, abdominal pain, nausea, and vomiting.
  • Initial diagnosis considered appendicitis due to symptoms.
  • The patient was admitted for further evaluation and management.

Findings:

  • The patient was diagnosed with classic Kawasaki disease.
  • The diagnosis was made in the context of confirmed coronavirus disease 2019 infection.
  • Standard Kawasaki disease treatment was initiated.

Implications:

  • This case highlights the importance of considering Kawasaki disease in children with fever and inflammation during the COVID-19 pandemic.
  • Prompt diagnosis and standard therapeutic interventions for Kawasaki disease are essential to prevent coronary artery aneurysms.
  • Clinicians should remain vigilant for these presentations in pediatric patients during the ongoing COVID-19 era.
Abstract

Keywords:
COVID-19KawasakiMultisystem inflammatory syndrome in children (MIS-C)

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