Related Experiment Video
Updated: Aug 22, 2025
07:50
Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model
Published on: September 3, 2020
4.7K
Ventricular septal rupture after delayed STEMI: A modern management approach
Muhammad Abubakar Shakir1, Vikashsingh P Rambhujun1, Erin A Fender1
1Department of Cardiology, Christiana Care Health System, Newark, Delaware, USA.
Journal of Cardiac Surgery
|November 10, 2022
Summary
Ventricular septal rupture (VSR) after myocardial infarction is serious. Early percutaneous VSR closure and mechanical support can stabilize patients for surgery, improving outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Ventricular septal rupture (VSR) is a rare but severe complication of myocardial infarction.
- Surgical repair is the standard treatment, but associated mortality rates remain high.
Observation:
- A 62-year-old male presented with ST-elevation myocardial infarction (STEMI) complicated by VSR and cardiogenic shock.
- The patient was managed with early percutaneous VSR closure, intra-aortic balloon pump, and inotropes.
Findings:
- This strategy facilitated hemodynamic stabilization and end-organ recovery.
- Percutaneous closure served as a successful bridge to definitive surgical VSR patch repair.
Implications:
- Mechanical circulatory support devices and percutaneous VSR closure can be crucial in managing VSR.
- A multidisciplinary structural heart team is essential for optimal patient outcomes.
Related Concept Videos
01:26Mitral Stenosis III: Medical Management
16
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
16
01:28Acute Coronary Syndrome IV: Interprofessional Care
22
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
22
01:25Aortic Regurgitation III: Medical Management
32
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
32
01:30Acute Coronary Syndrome I: Introduction
56
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
56
01:25Mitral Regurgitation III: Medical Management
25
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
25
01:27Mitral Stenosis IV: Nursing Management
27
A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
27