Progress in Probe-Based Sensing Techniques for In Vivo Diagnosis

Area of Science:

• Medical Robotics
• Biomedical Engineering
• Sensing Technologies

Background:

• Robotic surgery offers precise, minimally invasive endoluminal diagnosis and treatment.
• Miniaturized probe-based sensors integrated with medical robots improve procedural convenience and data acquisition.
• In vivo sensing technologies provide crucial physiological information during interventions.

Purpose of the Study:

• To review recent advancements in probe-based sensing techniques for in vivo physical and biochemical sensing.
• To highlight developments in China's research landscape for these technologies.
• To cover key sensing modalities including force, temperature, imaging, and chemical/biomarker detection.

Main Methods:

• Literature review focusing on Chinese research in probe-based in vivo sensing.
• Categorization of sensing techniques based on measured parameters (physical, biochemical).
• Analysis of sensor integration with medical robotic systems.

Main Results:

• Significant progress in developing various in vivo probe-based sensors for physical and biochemical sensing.
• Key areas of advancement include in vivo force sensing, temperature sensing, and advanced imaging techniques (OCT, photoacoustic, ultrasound).
• Emerging applications in chemical and biomarker sensing for enhanced diagnostic capabilities.

Conclusions:

• Probe-based sensing technologies are crucial for advancing robotic endoluminal interventions.
• Continued innovation in China is driving the development of sophisticated in vivo sensing solutions.
• These integrated technologies promise safer, more precise, and informative minimally invasive procedures.