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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Updated: Aug 22, 2025

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

Published on: May 25, 2022

COVID-19 Vaccine-Associated Ocular Adverse Effects: An Overview.

Parul Ichhpujani¹, Uday Pratap Singh Parmar¹, Siddharth Duggal¹

¹Department of Ophthalmology, Government Medical College and Hospital, Sector-32, Chandigarh 160030, India.

|November 11, 2022

Summary

This summary is machine-generated.

Ocular adverse effects following COVID-19 vaccination are reported but generally have a good prognosis. The benefits of vaccination outweigh the risks, though further research is needed to confirm causality.

Keywords:

COVID-19 vaccine booster molecular mimicry ocular adverse effects

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Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models

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Published on: March 16, 2022

Area of Science:

Ophthalmology
Vaccinology
Public Health

Background:

Global vaccination efforts against SARS-CoV-2 began in December 2020.
Ocular adverse effects following COVID-19 vaccination have been documented.

Purpose of the Study:

To review and report the onset interval and clinical presentations of ocular adverse effects after SARS-CoV-2 vaccination.
To synthesize reported ocular adverse events associated with various COVID-19 vaccines.

Main Methods:

A narrative review of English-language articles published between January 1, 2020, and September 1, 2022.
Inclusion of studies reporting ocular adverse effects linked to different COVID-19 vaccines.

Main Results:

Ocular adverse effects were reported for Pfizer (BNT162b2), Moderna (mRNA-1273), AstraZeneca (AZD-1222), and Johnson & Johnson (Ad26.COV2.S) vaccines.
Specific effects included graft rejection, keratitis, uveitis, ischemic optic neuropathy, retinal hemorrhages, and glaucoma.
Most reported ocular adverse events showed a good to fair prognosis with management.

Conclusions:

The benefits of SARS-CoV-2 vaccination outweigh the risks of ocular adverse effects, even in patients with pre-existing conditions.
A temporal association between vaccines and ocular events is suggested, but further investigation into causality and mechanisms is necessary.