Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-vendor multi-site quantitative MRI analysis of cartilage degeneration 10 Years after anterior cruciate ligament reconstruction: MOON-MRI protocol and preliminary results.

Osteoarthritis and cartilage·2022
Same author

Multi-vendor multi-site T<sub>1ρ</sub> and T<sub>2</sub> quantification of knee cartilage.

Osteoarthritis and cartilage·2020
Same author

Incidental imaging finding of chest wall mass.

Skeletal radiology·2015
Same author

Meniscus treatment and age associated with narrower radiographic joint space width 2-3 years after ACL reconstruction: data from the MOON onsite cohort.

Osteoarthritis and cartilage·2015
Same author

In vitro toxicity in long-term cell culture of MR contrast agents targeted to cartilage evaluation.

Osteoarthritis and cartilage·2014
Same author

Posterior horn medial meniscal root tear: the prequel.

Skeletal radiology·2014
Same journal

Retsat promotes synovial mesenchymal stem cell senescence and aggravates osteoarthritis by inhibiting the PPARγ/RXR heterodimerization pathway.

Osteoarthritis and cartilage·2026
Same journal

Effectiveness of a blended care intervention in physiotherapy with exercise and education for patients with hip or knee osteoarthritis (SmArt-E): A multicentre pragmatic randomized controlled trial.

Osteoarthritis and cartilage·2026
Same journal

Through the lens of light sheet, knee innervation shines.

Osteoarthritis and cartilage·2026
Same journal

Deep learning-based quantification of knee effusion-synovitis volume on MRI - Technique development and validation.

Osteoarthritis and cartilage·2026
Same journal

Mapping articular cartilage maturation across postnatal development by proteomics.

Osteoarthritis and cartilage·2026
Same journal

Effect of an oral complementary medicine combination for symptomatic knee osteoarthritis: A double-blind, randomized, placebo-controlled trial.

Osteoarthritis and cartilage·2026
See all related articles

Related Experiment Video

Updated: Aug 22, 2025

Measurement of Tumor T2* Relaxation Times after Iron Oxide Nanoparticle Administration
05:30

Measurement of Tumor T2* Relaxation Times after Iron Oxide Nanoparticle Administration

Published on: May 19, 2023

1.4K

Reproducibility of T1ρ and T2 quantification in a multi-vendor multi-site study.

R Lartey1, A Nanavati1, J Kim1

  • 1Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, OH, USA; Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, OH, USA.

Osteoarthritis and Cartilage
|November 12, 2022
PubMed
Summary
This summary is machine-generated.

This study shows excellent reproducibility for 2D MESE T2 mapping and longitudinal 3D MAPSS T1ρ and T2 mapping across multiple MRI vendors and sites. These findings support the use of these techniques for consistent cartilage quantification.

Keywords:
Cartilage imagingMagnetic resonance imagingRepeatabilityReproducibilityT(1ρ)T(2)

More Related Videos

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

19.6K
Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
06:33

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

11.4K

Related Experiment Videos

Last Updated: Aug 22, 2025

Measurement of Tumor T2* Relaxation Times after Iron Oxide Nanoparticle Administration
05:30

Measurement of Tumor T2* Relaxation Times after Iron Oxide Nanoparticle Administration

Published on: May 19, 2023

1.4K
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

19.6K
Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
06:33

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

11.4K

Area of Science:

  • Radiology
  • Biomedical Engineering
  • Medical Imaging

Background:

  • Quantitative MRI techniques like T2 mapping and T1ρ mapping are crucial for cartilage assessment.
  • Evaluating the reproducibility of these techniques across different vendors and sites is essential for clinical translation.

Purpose of the Study:

  • To assess the multi-vendor, multi-site reproducibility of 2D multi-echo spin-echo (MESE) T2 mapping.
  • To evaluate the longitudinal reproducibility of 3D magnetization-prepared angle-modulated partitioned k-space spoiled gradient echo snapshots (MAPSS) T1ρ and T2 mapping, and 2D MESE T2 mapping over 6 months.

Main Methods:

  • Phantoms and 20 volunteers were scanned on four 3T MRI systems from three vendors across four sites.
  • Two traveling volunteers underwent scans at all sites at baseline and 6-month follow-up.
  • Coefficients of variation (CVs) were calculated to determine intra-site and inter-site reproducibility.

Main Results:

  • For 2D MESE T2, baseline intra-site CVs ranged from 3.15-8.49% for volunteers, and inter-site CVs were 14.16%.
  • Longitudinal intra-site CVs for volunteers were 2.60-4.86% for 3D MAPSS T1ρ, 3.33-7.25% for 3D MAPSS T2, and 3.11-8.77% for 2D MESE T2.
  • Phantoms showed excellent intra-site reproducibility for all sequences (CVs < 3.56%).

Conclusions:

  • 2D MESE T2 imaging demonstrates excellent intra-site reproducibility.
  • Longitudinal T1ρ and T2 cartilage quantification using both 2D MESE T2 and 3D MAPSS T1ρ/T2 sequences show excellent reproducibility in a multi-vendor, multi-site setting.
  • Inter-site variation for 2D MESE T2 was slightly higher than for 3D MAPSS T2.