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Updated: Aug 22, 2025
Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores
Published on: April 5, 2022
A cyclodextrin-based turn-off fluorescent probe for naked-eye detection of copper ions in aqueous solution
Jin Wang1, Xiao-Qin Yang1, Na Li1
1School of Pharmacy, Jiangsu Province Engineering Research Centre of Tumor Targeted Nano Diagnostic and Therapeutic Materials, Yancheng Teachers University, Yancheng 224007, Jiangsu Province, China.
Abstract:
A novel fluorescent probe L consisting of β-Cyclodextrin (β-CD) and thiosemicarbazide moieties was designed for copper ions detection. Apparent fluorescence quenching of probe L in Tris-HCl（pH = 7.4）solution was observed only in the presence of Cu2+, among other interfering ions. The present probe L was 1:1 complexed with Cu2+ and the detection limit of probe L was calculated to be 1.37 μM. The results demonstrate that the probe L may provide a convenient method for visual detection of Cu2+ in the environmental and biological systems.
