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Updated: Aug 22, 2025

Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Global variation in skin injures and skincare practices in extremely preterm infants
Pranav Jani1,2, Umesh Mishra3,4, Julia Buchmayer5
1Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia. Pranav.Jani@sydney.edu.au.
Insights
Skin injuries like diaper dermatitis and those from medical adhesives are common in extremely preterm infants. Consistent skincare guidelines and regular assessments significantly reduce these occurrences.
Area of Science:
- Neonatal care
- Dermatology
- Public health
Background:
- Extremely preterm infants are highly susceptible to skin injuries.
- Global variations exist in skincare practices and injury incidence among these vulnerable infants.
- Understanding these variations is crucial for developing standardized care protocols.
Purpose of the Study:
- To describe the types and prevalence of skin injuries in extremely preterm infants worldwide.
- To document current skincare practices in neonatal intensive care units (NICUs).
- To investigate the association between specific skincare practices and the occurrence of skin injuries.
Main Methods:
- A global web-based survey was conducted from February 2019 to August 2021.
- Data on skin injuries and skincare practices were collected from 848 NICUs across diverse regions and income levels.
- Statistical analysis, including multivariable logistic regression, was used to identify associations, adjusted for regional factors.
Main Results:
- Diaper dermatitis (39%) and medical adhesive-related skin injuries (38%) were the most prevalent injuries.
- Adherence to local skincare guidelines was associated with a significant reduction in multiple types of skin injuries.
- Performing skin assessments every four hours or more frequently decreased the incidence of abrasions, pressure injuries, diaper dermatitis, and perineal injuries.
Conclusions:
- Skin injuries are a significant concern in extremely preterm infants globally.
- Implementing consistent skincare guidelines and enhancing surveillance through regular assessments can effectively reduce skin injury rates.
- Further research is needed to establish optimal evidence-based practices and minimize variations in care to improve infant outcomes.
Background:
Globally, are skincare practices and skin injuries in extremely preterm infants comparable? This study describes skin injuries, variation in skincare practices and investigates any association between them.
Methods:
A web-based survey was conducted between February 2019 and August 2021. Quantifying skin injuries and describing skincare practices in extremely preterm infants were the main outcomes. The association between skin injuries and skincare practices was established using binary multivariable logistic regression adjusted for regions.
Results:
Responses from 848 neonatal intensive care units, representing all geographic regions and income status groups were received. Diaper dermatitis (331/840, 39%) and medical adhesive-related skin injuries (319/838, 38%) were the most common injuries. Following a local skincare guideline reduced skin injuries [medical adhesive-related injuries: adjusted odds ratios (aOR) = 0.63, 95% confidence interval (CI) = 0.45-0.88; perineal injuries: aOR = 0.66, 95% CI = 0.45-0.96; local skin infections: OR = 0.41, 95% CI = 0.26-0.65; chemical burns: OR = 0.46, 95% CI = 0.26-0.83; thermal burns: OR = 0.51, 95% CI = 0.27-0.96]. Performing skin assessments at least every four hours reduced skin injuries (abrasion: aOR = 0.48, 95% CI = 0.33-0.67; pressure: aOR = 0.51, 95% CI = 0.34-0.78; diaper dermatitis: aOR = 0.71, 95% CI = 0.51-0.99; perineal: aOR = 0.52, 95% CI = 0.36-0.75). Regional and resource settings-based variations in skin injuries and skincare practices were observed.
Conclusions:
Skin injuries were common in extremely preterm infants. Consistency in practice and improved surveillance appears to reduce the occurrence of these injuries. Better evidence regarding optimal practices is needed to reduce skin injuries and minimize practice variations.
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