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Comparison between two viscosupplementation protocols for temporomandibular joint osteoarthritis
Natália R Ferreira1,2, Aleli T Oliveira2, Carolina Kaminski Sanz3,4
1University of Coimbra, Institute for Occlusion and Orofacial Pain, Faculty of Medicine, Coimbra, Portugal.
Objective:
This clinical trial aimed to compare the efficacy of two protocols using high molecular weight hyaluronic acid (HA) intra-articular injection in patients with temporomandibular joint (TMJ) osteoarthritis and evaluate involvement of subchondral bone changes and psychosocial factors as predictors of HA treatment.
Methods:
Twenty-one individuals were divided into two groups: (A) received three intra-articular HA injections, and (B) received one injection. Outcomes observed were pain intensity, functional limitation, maximum voluntary mouth opening, maximum assisted mouth opening, and treatment tolerability. Follow-ups were performed weekly for 21 days, and two months after the treatment started.
Results:
No statistically significant intergroup differences were observed in any of the evaluated outcomes. However, Group A showed significant improvement in all outcomes, whereas Group B showed significant improvement only in pain intensity and functional limitation.
Conclusion:
This study demonstrated the effectiveness of both protocols in terms of pain intensity and functional limitation caused by osteoarthritis.
