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Viral Recombination

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

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Related Experiment Video

Updated: Aug 22, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

Monkeypox Virus Infections in Humans.

Sameer Elsayed^1,2,3, Lise Bondy¹, William P Hanage⁴

¹Department of Medicine, Western University, London, Ontario, Canada.

Clinical Microbiology Reviews

|November 14, 2022

Summary

This summary is machine-generated.

Human monkeypox, a viral zoonosis, is spreading globally. This review covers its origins, virology, clinical signs, diagnostics, and public health strategies for this emerging infectious disease.

Keywords:

Monkeypox virus Orthopoxvirus immunization monkeypox outbreak public health tecovirimat virology

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Last Updated: Aug 22, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2

Published on: April 10, 2009

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 3

Published on: April 13, 2009

Area of Science:

* Epidemiology and Virology
* Public Health and Infectious Diseases

Background:

* Human monkeypox is a viral zoonosis originating in West and Central Africa.
* Recent global spread has raised concerns as an emerging infectious disease threat.
* Characterized by flu-like symptoms and a smallpox-like rash.

Purpose of the Study:

* To review the origins, virology, and epidemiology of monkeypox virus.
* To discuss clinical manifestations, diagnostics, and management strategies.
* To outline public health interventions and future research directions.

Main Methods:

* Comprehensive literature review of monkeypox outbreaks and research.
* Analysis of epidemiological data and virological studies.
* Synthesis of information on clinical presentation and public health responses.

Main Results:

* Documented human-to-human transmission in non-endemic countries.
* Established link between monkeypox and smallpox eradication efforts.
* Identified key clinical features and diagnostic approaches.

Conclusions:

* Monkeypox represents a significant emerging infectious disease requiring global attention.
* Effective public health interventions are crucial for containment.
* Further research is needed to understand and manage future outbreaks.