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Nanostructured Ag-zeolite Composites as Luminescence-based Humidity Sensors
Published on: November 15, 2016
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Application of zeolites and zeolitic imidazolate frameworks in the biosensor development
I S Kucherenko1, O O Soldatkin2, S V Dzyadevych2
1Institute of Molecular Biology and Genetics, NAS of Ukraine, 150 Zabolotnogo str., 03143 Kyiv, Ukraine; IQVIA, 12 Amosova str., 03038 Kyiv, Ukraine.
Biomaterials Advances
|November 14, 2022
Summary
Zeolites and zeolitic imidazolate frameworks (ZIFs) enhance biosensor performance. These nanomaterials improve sensitivity and detection limits for analyzing various media, paving the way for advanced biosensor applications.
Area of Science:
- Nanomaterials Science
- Analytical Chemistry
- Biotechnology
Background:
- Biosensors are crucial for analyzing diverse samples like blood, urine, and environmental media.
- Current biosensor development heavily relies on advanced nanomaterials, specifically zeolites and zeolitic imidazolate frameworks (ZIFs).
Purpose of the Study:
- To review electrochemical and optical biosensors utilizing zeolites and ZIFs in their biorecognition elements.
- To explore the advantages of employing zeolites and ZIFs in biosensor design and application.
Main Methods:
- Review of electrochemical (amperometric, conductometric, ISFET) and optical (fluorescent, colorimetric) biosensor configurations.
- Analysis of biosensors incorporating immobilized enzymes, antibodies, DNA, and aptamers on zeolites and ZIFs.
Main Results:
- Zeolite- and ZIF-containing biosensors demonstrate enhanced sensitivity, improved limits of detection, and wider linear ranges compared to conventional biosensors.
- Immobilization of biomolecules onto zeolites and ZIFs facilitates the creation of advanced biosensors with superior analytical characteristics.
Conclusions:
- Zeolites and ZIFs are highly effective nanomaterials for developing next-generation biosensors.
- These advanced biosensors hold significant potential for future research and practical implementation in various analytical fields.
