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Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
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Periprocedural myocardial infarction in patients undergoing percutaneous coronary intervention

Yasushi Ueki1, Koichiro Kuwahara1

  • 1Department of Cardiovascular Medicine, Shinshu University Hospital, Nagano, Japan.

Journal of Cardiology
|November 14, 2022
PubMed

Insights

Percutaneous coronary intervention (PCI) reduces risks but can cause myocardial injury. Accurately diagnosing periprocedural myocardial infarction (MI) is crucial for patient management and clinical trials.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Biomarker Analysis

Background:

  • Percutaneous coronary intervention (PCI) improves outcomes but carries a risk of periprocedural myocardial infarction (MI).
  • Existing research explores mechanisms, predictors, and treatments for PCI-related MI.
  • Varied definitions of periprocedural MI exist, impacting reported frequency and significance.

Purpose of the Study:

  • To review the mechanisms, predictors, frequency, and prognostic impact of periprocedural MI.
  • To discuss the current perspectives on diagnosing and managing periprocedural MI.
  • To highlight the importance of consistent definitions for clinical trials and practice.

Main Methods:

  • Literature review of studies on periprocedural MI.
  • Analysis of different proposed definitions for periprocedural MI.
  • Synthesis of data on frequency, predictors, and outcomes.

Main Results:

  • PCI reduces spontaneous MI and revascularization needs but increases periprocedural MI risk.
  • Definitions of periprocedural MI vary significantly, affecting clinical interpretation.
  • Accurate diagnosis is vital for patient management and clinical trial endpoints.

Conclusions:

  • Standardized, clinically relevant definitions are needed for periprocedural MI.
  • Understanding periprocedural MI is essential for optimizing PCI outcomes.
  • Further research should focus on consistent diagnostic criteria and prognostic implications.

Keywords:
Chronic coronary syndromeMyocardial infarctionMyocardial injuryPercutaneous coronary intervention

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