Janus Micro/Nanorobots in Biomedical Applications.

Area of Science:

• Materials Science
• Biomedical Engineering
• Nanotechnology

Background:

• Janus particles feature distinct domains, enabling diverse functionalities within a single entity.
• Micro/nanorobots convert energy into precise movement, showing potential in targeted applications.
• Integrating Janus structures with micro/nanorobots offers novel solutions for biomedicine.

Purpose of the Study:

• To review the fabrication and energy sources of Janus micro/nanorobots.
• To discuss recent advancements in biomedical applications of Janus micro/nanorobots.
• To identify challenges and potential solutions for clinical translation.

Main Methods:

• Literature review of fabrication techniques for Janus micro/nanorobots.
• Analysis of energy sources powering these micro/nanorobots.
• Synthesis of recent research on biomedical applications.

Main Results:

• Janus micro/nanorobots are fabricated using various methods and powered by diverse energy sources.
• Key applications include targeted cargo delivery, enhanced bioimaging, sensitive biosensing, precise surgery, and innovative therapies.
• Significant challenges remain in fabrication scalability, engine efficiency, biocompatibility, and biodegradation.

Conclusions:

• Janus micro/nanorobots show immense promise for revolutionizing biomedical applications.
• Overcoming fabrication, biocompatibility, and biodegradation hurdles is crucial for clinical adoption.
• Emerging materials and strategies offer promising avenues for future development.