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A novel pyrene-based fluorescent probe for Al3+ detection.

Yulong Liu1, Yeqi Zhang1, Ming Sheng1

  • 1Department of Chemistry, College of Arts and Sciences, Northeast Agricultural University, 600 Changjiang Road, Harbin 150030, China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
|November 15, 2022
PubMed
Summary

A new fluorescent probe, PAI, specifically detects aluminum ions (Al3+) with high sensitivity. This "turn-on" probe offers a low detection limit, enabling effective Al3+ sensing applications.

Keywords:
Al(3+)C=N double bondFluorescent probePyrene fluorophoreTest paper

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Area of Science:

  • Analytical Chemistry
  • Materials Science
  • Organic Chemistry

Background:

  • Schiff base chemistry is a versatile platform for designing functional molecules.
  • Pyrene derivatives are widely used in fluorescent probes due to their photophysical properties.
  • Selective detection of aluminum ions (Al3+) is crucial in various environmental and biological applications.

Purpose of the Study:

  • To design and synthesize a novel fluorescent probe for Al3+ detection.
  • To investigate the sensing mechanism and performance of the probe.
  • To evaluate the probe's applicability in practical sensing scenarios.

Main Methods:

  • Synthesis of dimethyl 5-((pyren-1-ylmethylene)amino)isophthalate (PAI) via Schiff base reaction.
  • Structural characterization using FT-IR, 1H NMR, 13C NMR, and HRMS.
  • Fluorescence spectroscopy to study the interaction with Al3+ and determine the limit of detection.

Main Results:

  • The synthesized PAI probe exhibits a "turn-on" fluorescence response selective for Al3+.
  • High sensitivity was achieved with a limit of detection of 3.07 × 10-8 M.
  • The sensing mechanism involves the disruption of photoinduced electron transfer (PET) upon Al3+ binding.
  • PAI demonstrated potential for Al3+ detection using test papers.

Conclusions:

  • PAI is a highly sensitive and selective fluorescent probe for Al3+ detection.
  • The probe's mechanism relies on the inhibition of PET, leading to enhanced fluorescence.
  • PAI shows promise for practical applications in Al3+ sensing, including field tests.