Scenarios in precision medicine: proteomics in heart failure

Piero Gentile1, Matteo Palazzini1, Andrea Garascia1

  • 1De Gasperis Cardio Center, Niguarda Hospital, Milan.

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Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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Pathophysiology of Heart Failure

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These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
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