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Published on: September 26, 2018
Cardiovascular prevention: sometimes dreams can come true
Roberto Ferrari1, Paolo Cimaglia2, Claudio Rapezzi1,2
1Cardiovascular Research Centre, Ferrara University, Via Aldo Moro 8, Ferrara 44124, Italy.
Insights
Future cardiovascular disease (CVD) prevention requires a paradigm shift towards personalized, technology-driven strategies. This involves integrating genetic insights, environmental exposure data, and a proactive
Area of Science:
- Cardiovascular Medicine
- Preventive Cardiology
- Public Health
Background:
- Cardiovascular disease (CVD) is a multifactorial chronic condition where prevention is increasingly critical as treatments plateau.
- The COVID-19 pandemic exposed significant limitations in current healthcare systems, particularly in preventive medicine and territorial health.
- Recent advancements include the SCORE2 risk prediction algorithm and updated European guidelines for CVD prevention.
Purpose of the Study:
- To envision a future model for cardiovascular disease (CVD) prevention.
- To explore novel concepts and paradigms for proactive and personalized CVD risk management.
- To outline essential components for achieving an ideal CVD prevention system.
Main Methods:
- Review article synthesizing current knowledge and future perspectives on CVD prevention.
- Discussion of emerging concepts: genetically personalized risk, imaging-driven factors, cardiac risk cartography, and exposome measurement.
- Analysis of economic factors (cost of delayed outcomes vs. healthy lifespan) and technological integration.
Main Results:
- Highlights the need for a shift from a 'sick' to a 'healthy' system, emphasizing patient engagement.
- Proposes a 'clearing house' model with a multidisciplinary 'healthcare team' rather than a specialized 'heart team'.
- Identifies key technological and conceptual advancements required for future prevention strategies.
Conclusions:
- Future CVD prevention necessitates a holistic, personalized, and technologically advanced approach.
- A proactive healthcare system focused on well-being, integrating diverse data, is essential.
- Achieving this vision requires addressing four critical, articulated points for implementation.
Abstract:
Cardiovascular disease (CVD) is a chronic condition driven by the complex interaction of different risk factors including genetics, lifestyle, environment, etc. which, differently from other pathologies, can be prevented. Treatment of CVD has been inconceivably successful but now it seems that it has reached a plateau suggesting that prevention is the way forward. However, the COVID-19 pandemic has spotted all the limits of the actual health system regarding territorial and, particularly, of preventive medicine. To this end, recently, the SCORE2 risk prediction algorithms, a contemporary model to estimate 10-years risk of CVD in Europe and the new guidelines on prevention have been released. The present review article describes a dream: how prevention of CVD should be addressed in the future. New concepts and paradigms like early genetically personalized and imaging driven risk factors, cardiac risk cartography, measurements of the exposome, estimation of costs of a delayed outcome vs. healthy lifespan, are all addressed. We highlight the importance of technologies and the concept of being engaged in a 'healthy' and not just 'sick' system as it is today. The concept of 'clearing house' with a 'healthcare team' instead of a 'heart team' is described. Finally, we articulate the four points necessary for the dream to come true.
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