Cardiovascular prevention: sometimes dreams can come true

Roberto Ferrari1, Paolo Cimaglia2, Claudio Rapezzi1,2

  • 1Cardiovascular Research Centre, Ferrara University, Via Aldo Moro 8, Ferrara 44124, Italy.

Insights

Future cardiovascular disease (CVD) prevention requires a paradigm shift towards personalized, technology-driven strategies. This involves integrating genetic insights, environmental exposure data, and a proactive

Area of Science:

  • Cardiovascular Medicine
  • Preventive Cardiology
  • Public Health

Background:

  • Cardiovascular disease (CVD) is a multifactorial chronic condition where prevention is increasingly critical as treatments plateau.
  • The COVID-19 pandemic exposed significant limitations in current healthcare systems, particularly in preventive medicine and territorial health.
  • Recent advancements include the SCORE2 risk prediction algorithm and updated European guidelines for CVD prevention.

Purpose of the Study:

  • To envision a future model for cardiovascular disease (CVD) prevention.
  • To explore novel concepts and paradigms for proactive and personalized CVD risk management.
  • To outline essential components for achieving an ideal CVD prevention system.

Main Methods:

  • Review article synthesizing current knowledge and future perspectives on CVD prevention.
  • Discussion of emerging concepts: genetically personalized risk, imaging-driven factors, cardiac risk cartography, and exposome measurement.
  • Analysis of economic factors (cost of delayed outcomes vs. healthy lifespan) and technological integration.

Main Results:

  • Highlights the need for a shift from a 'sick' to a 'healthy' system, emphasizing patient engagement.
  • Proposes a 'clearing house' model with a multidisciplinary 'healthcare team' rather than a specialized 'heart team'.
  • Identifies key technological and conceptual advancements required for future prevention strategies.

Conclusions:

  • Future CVD prevention necessitates a holistic, personalized, and technologically advanced approach.
  • A proactive healthcare system focused on well-being, integrating diverse data, is essential.
  • Achieving this vision requires addressing four critical, articulated points for implementation.

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