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Updated: Aug 21, 2025

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Intraportal Transplantation of Pancreatic Islets in Mouse Model
Published on: May 5, 2018
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Bone marrow chimerism breaks the barrier to pancreatic islet transplantation
Laura Crisa1, Vincenzo Cirulli1
1Department of Medicine, Department of Pharmacology, UW Diabetes Institute, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
Cell Reports
|November 17, 2022
Abstract:
In their recent Cell Reports paper, Chang and colleagues report on a successful strategy to achieve durable mixed hematopoietic chimerism that promotes the engraftment and long-term function of pancreatic islet allotransplants in fully immunocompetent mice without immunosuppression.

