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Updated: Aug 21, 2025
08:00
Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
Published on: October 4, 2024
665
Development and application of light-controlled inducible recombination systems
Tian Xie1, Mei Wang1, Rui-Yu Gao1
1Genome Tagging Project Center, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China.
Yi Chuan = Hereditas
|November 17, 2022
Summary
Light-controlled inducible recombination systems offer precise gene manipulation using photocages or optogenetics. These advanced tools enable spatiotemporal control for gene function research and disease treatment.
Area of Science:
- Molecular Biology
- Genetics
- Biotechnology
Background:
- Site-specific recombination systems are crucial for gene manipulation in life sciences.
- Inducible recombination systems allow precise spatiotemporal regulation of gene expression.
- Existing systems include chemical-controlled and light-controlled methods.
Conclusions:
- Light-controlled inducible recombination systems provide advanced tools for complex biological research.
- These systems enhance possibilities for studying gene function and developing therapies.
- Further optimization and development are expected to meet evolving research demands.
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