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Preparing European Nephrology for the next pandemic: lessons from the ERACODA collaboration
Priya Vart1,2, Raphaël Duivenvoorden3, Casper F M Franssen1
1Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Insights
The COVID-19 pandemic devastated kidney disease patients. Lessons learned from the ERACODA project highlight the need for better collaboration and data infrastructure to prepare nephrology for future infectious disease outbreaks.
Area of Science:
- Nephrology
- Infectious Diseases
- Public Health
Background:
- Patients with chronic kidney disease are highly vulnerable to infectious diseases.
- The coronavirus disease 2019 (COVID-19) pandemic severely impacted the nephrology community.
- Future pandemics or infectious disease outbreaks remain a significant threat.
Purpose of the Study:
- To draw lessons from the European Renal Association COVID-19 Database (ERACODA) project.
- To identify challenges in generating evidence for managing kidney disease patients during pandemics.
- To provide recommendations for future pandemic preparedness in European nephrology.
Main Methods:
- Analysis of the ERACODA project, a pan-European collaboration initiated in March 2020.
- Understanding the prognosis of COVID-19 in patients on kidney replacement therapy.
- Review of challenges in evidence generation and data quality.
Main Results:
- The COVID-19 pandemic exposed shortcomings in pandemic response within nephrology.
- Limited collaboration, lack of common data architecture, and suboptimal data quality hindered the response.
- The ERACODA project provided insights into COVID-19's impact on kidney function replacement therapy patients.
Conclusions:
- Improved collaboration and standardized data architecture are crucial for future pandemic responses.
- Strengthening electronic health records and involving experts in study design are recommended.
- The European Renal Association can lead in aligning research initiatives for enhanced preparedness.
Abstract:
Owing to the vulnerability of patients with chronic kidney disease to infectious diseases, the coronavirus disease 2019 (COVID-19) pandemic has been particularly devastating for the nephrology community. Unfortunately, the possibility of future COVID-19 waves or outbreaks of other infectious diseases with pandemic potential cannot be ruled out. The nephrology community made tremendous efforts to contain the consequences of the COVID-19 pandemic. Despite this, the COVID-19 pandemic has highlighted several shortcomings in our response to the pandemic and has taught us important lessons that can be utilized to improve our preparedness for any future health crises of a similar nature. In this article we draw lessons from the European Renal Association COVID-19 Database (ERACODA) project, a pan-European collaboration initiated in March 2020 to understand the prognosis of COVID-19 in patients on kidney function replacement therapy. We discuss the challenges faced in generating timely and robust evidence for informed management of patients with kidney disease and give recommendations for our preparedness for the next pandemic in Europe. Limited collaboration, the absence of common data architecture and the sub-optimal quality of available data posed challenges in our response to COVID-19. Aligning different research initiatives, strengthening electronic health records, and involving experts in study design and data analysis will be important in our response to the next pandemic. The European Renal Association may take a leading role in aligning research initiatives via its engagement with other scientific societies, national registries, administrators and researchers.
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