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Prostate primary intravascular large B-cell lymphoma: A case report.
Lijuan Gu1, Menghui Li2, Guizhen Tong1
1Department of Pathology, Peking University Third Hospital YanQing Hospital, Beijing, 102100, China.
Urology Case Reports
|November 17, 2022
Summary
Intravascular large B-cell lymphoma (IVLBCL) is a rare cancer affecting elderly individuals. This case highlights a unique presentation of IVLBCL in the prostate, emphasizing diagnostic importance.
Area of Science:
- Oncology
- Hematology
- Pathology
Background:
- Intravascular large B-cell lymphoma (IVLBCL) is a rare extranodal diffuse large B-cell lymphoma (DLBCL) subtype.
- It characteristically involves neoplastic cell infiltration within small blood vessel lumina, primarily affecting older adults.
Observation:
- A 76-year-old male presented with severe lower urinary tract obstruction symptoms.
- Diagnosis of IVLBCL was established via histopathological and immunohistochemical analysis of prostate tissue obtained during transurethral resection.
Findings:
- This report details an extremely rare instance of primary IVLBCL originating in the prostate.
- The diagnostic process relied on detailed examination of prostate biopsy specimens.
Implications:
- Accurate and timely diagnosis of prostate IVLBCL is crucial for effective patient management.
- Increased awareness among clinicians can improve diagnostic formulation and treatment planning for this rare condition.

