Erasmus Syndrome: A Rare Occupational Disease
Related Experiment Video
Updated: Aug 21, 2025

Mouse Model of Oleic Acid-Induced Acute Respiratory Distress Syndrome
Published on: June 2, 2022
Vildan Manav1, Elif B Avcı1, Ozan Erdem1
1Department of Dermatology, İstanbul Training and Research Hospital, İstanbul, Turkey.
Abstract:
Erasmus syndrome is a rare syndrome accompanied by interstitial lung disease and scleroderma caused by silica exposure. There are a limited number of case reports in the literature. Awareness of this rare syndrome is important and occupational exposure should be questioned in patients presenting with scleroderma in our country, silica exposure is quite frequent and it should be kept in mind. Here, we report a case of a 41-year-old male patient presenting with interstitial lung disease, scleroderma, and serpiginous supravenous hypermelanosis caused by silica exposure who worked in the denim grinding for a short period of three months.
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