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Updated: Aug 21, 2025

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Cardiac venous malformation concurrent with multiple hepatic venous malformations: A case report
Shijie Zhang1, Zhenqiang Xu1,2, Chengwei Zou1,2
1Department of Cardiovascular Surgery, Shandong Provincial Hospital, Shandong University, Jinan, China.
A cardiac mass was suspected to be a venous malformation in a patient with hepatic venous malformations. Surgical resection and pathology confirmed the cardiac venous malformation diagnosis, highlighting a rare presentation.
Area of Science:
- Cardiovascular Medicine
- Vascular Surgery
- Diagnostic Imaging
Background:
- A 50-year-old woman with a history of right radical mastectomy presented with exertional dyspnea and chest tightness.
- Initial investigations revealed a cardiac mass and multiple hepatic lesions.
Observation:
- Hepatic lesions were biopsied, and histopathology confirmed them as venous malformations.
- Imaging findings and literature review suggested the cardiac mass was also a venous malformation.
Findings:
- The cardiac mass was surgically resected.
- Postoperative pathology confirmed the cardiac mass to be a venous malformation, aligning with the hepatic lesions.
Implications:
- This case highlights the potential for cardiac venous malformations to occur concurrently with hepatic venous malformations.
- It underscores the importance of considering rare vascular anomalies in the differential diagnosis of cardiac masses, especially in patients with a history of malignancy or other vascular lesions.
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