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Updated: Aug 21, 2025

Electrochemical Impedance Spectroscopy as a Tool for Electrochemical Rate Constant Estimation
Published on: October 10, 2018
Electrochemical reduction of nitrobenzene via redox-mediated chronoamperometry
Athanasios D Stergiou1, Daniel H Broadhurst1, Mark D Symes1
1WestCHEM, School of Chemistry, University of Glasgow, University Avenue, Glasgow G12 8QQ, UK.
Abstract:
Anilines are important feedstocks for pharmaceuticals, dyes, and other materials, but traditional approaches to their syntheses usually lack selectivity and environmental sustainability. Here, we describe the selective reduction of nitrobenzene to aniline under mild conditions, using water as the ultimate source of the required protons and electrons. We describe the electrochemical cell assembly, and detail steps for electrochemical reduction followed by organic extraction and analysis of the extracts using NMR. For complete details on the use and execution of this protocol, please refer to Stergiou and Symes (2022a).
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